Description
Mouse NF-kB/SEAP reporter cell line can be used for screening of TLR agonists or antagonists as well as inhibitory TLR antibody assay. RAW 264.7 cells are known to respond to most Toll-like receptor (TLR) ligands, which trigger the NF-kB induction and lead to inflammatory cytokine production. The recombinant form of placental alkaline phosphatase (secreted alkaline phosphatase, SEAP) is used for reporter gene function.
Full Name
Mouse NF-kB/SEAP reporter Cell Line
Parental Cell Line
RAW264.7
Adherent Suspension
Macrophage
Suggested Medium
Growth Medium: IMDM, 10% FBS; Freeze Medium: IMDM, 20% FBS, 10% DMSO
Storage
The cell line is shipped using dry ice. Upon arrival, it should be stored in liquid nitrogen vapor phase
Warranty
Our KO cell line products are for research use only.
