Description
Established by EBV transformation of mononuclear cells from the peripheral blood of a 13 year old female with Ataxia telangiectasia (AT) complementation group C. AT cell line is a rare autosomal recessive disorder. Lymphocytes have been shown to be hypersensitive to cytotoxic and clastogenic effects of gamma and X rays. T cells from the same original sample have been used for studies of mutant frequency at the hprt locus, with cells being described as Donor 58 or Patient 2 (see Lancet 1985). Fibroblasts derived from the same individual were reported to have RNA and genomic DNA sequence changes (del, 9nt).
Adherent Suspension
Suspension
Suggested Medium
RPMI 1640 + 4mM Glutamine + 200 µg/ml Sodium Pyruvate (NaPy) + 15% Heat Inactivated (HI-FBS).
Quality Control
LB58 Cell Line was tested and found to be free of mycoplasma, bacterial, viruses, and other toxins. All cells were above 95% viability before freezing.
Morphology
Lymphoblastoid
Shippment
LB58 Cell Line will be shipped using dry ice.
Storage
Store the cell lines in liquid nitrogen vapor (less than -130°C)
Warranty
LB58 Cell Line is for research use only
