Description
This cell line expresses a surface human GITR (glucocorticoid-induced TNFR family related gene; TNFRSF18; CD357) and an NF-ĸB luciferase reporter construct that are stably integrated into the genome of Jurkat T-cells. The firefly luciferase gene is controlled by 4 copies of NF-kB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-ĸB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene.
Parental Cell Line
Jurkat
Shippment
The reporter cell line is shipped using dry ice.
Storage
Upon arrival, Store the cell lines in liquid nitrogen vapor (less than -130°C)
Warranty
For Research Use Only